- Provides the active form of folate (L-5-MTHF)
- Supports the synthesis of serotonin, dopamine and noradrenaline
- Supports mood stability and stress resistance
- Helps reduce fatigue when folate status is low
Methylated Folate
60 capsules, 1 per day
Methylated folateSupport for votingL-5-MTHFCognitive healthActive folateMethylation supportSynthesis of neurotransmittersEnergy and Burnout SupportSupport for folate deficiency
The basis of well-being, made pure
Ingredients
- Capsuleomhulsel[YOUR DOSE] mcg L-5-methyltetrahydrofolate (L-5-MTHF) per capsule
- Methylated Folate (als 5-MTHF)
Mood and Emotional Balance
Neurotransmitter Support
Methylation cycle
Key Benefits
- Active folate for methylation
- Mood and emotional balance
- Synthesis of neurotransmitters (serotonin, dopamine, noradrenaline)
- Energy & Burnout Support
- Cellular and cognitive health
Backed by science and rooted in nature
Mood & neurotransmitters L-5-MTHF is the active form of folate that your body can use directly to produce neurotransmitters like serotonin, dopamine, and norepinephrine. If you have low folate status or a less efficient MTHFR enzyme, this activated form can help better support the production of these mood chemicals. It is not a replacement for depression treatment but can complement a broader plan for mood and mental resilience.
Energy & fatigue Folate is involved in energy metabolism and the conversion of nutrients into usable cellular energy. When your folate levels are low, you may feel exhausted or "flat" more quickly. L-5-MTHF directly supports these processes because it doesn't need to be converted first. Many people experience a gradual improvement in daily energy fluctuations and less "severe" mental fatigue when supplementing.
Cognitive clarity The active form of folate plays a role in brain processes necessary for concentration, mental clarity, and information processing. By supporting neurotransmitter synthesis and one-carbon metabolism, L-5-MTHF helps the brain function more efficiently, especially in people with suboptimal folate intake. The effects are subtle and typically build over 1–4 weeks; so expect more "steady and clear" than a stimulating, nervous focus.
Folate status & homocysteine Folate helps convert homocysteine ​​into other substances. Research links elevated homocysteine ​​levels to cardiovascular and possibly brain health. L-5-MTHF, along with B12 and B6, can help maintain folate status and support a healthy homocysteine ​​balance. This is especially relevant for people with a known folate deficiency or elevated homocysteine, in consultation with their healthcare provider. The cycle influences the production of serotonin, dopamine, and norepinephrine.
Clinically Researched Benefits of Folate for Mood
Mood and Depression Support
- Supports the synthesis of serotonin, dopamine, and norepinephrine by supplying readily available folate to brain cells.
- In some clinical trials, L-methylfolate as an addition to antidepressants has been shown to further reduce mood symptoms in people with a low folate status; this is an add-on option, not a stand-alone treatment.
Cognitive and Brain Health
- Contributes to normal energy metabolism; good folate status is associated with less subjective fatigue and brain fog.
- In people with folate deficiency or increased needs, supplementation within 1–4 weeks can contribute to a more stable mood and less fatigue, although the response varies from person to person.
Methylation and Energy
- Supports cognitive functions such as concentration and mental clarity through one-carbon metabolism and neurotransmitters.
- Studies suggest that activated folate produces small but noticeable improvements in processing speed and cognitive efficiency in some participants, especially when folate levels were low.
Unlock Foundational Immunity, Bone Strength and Balance
Active folate (L-5-MTHF) which supports the methylation cycle, neurotransmitter production and clear thinking.
Neurotransmitter and mood support
Provides the active form of folate which is used to produce important neurotransmitters such as serotonin, dopamine and norepinephrine, thus supporting mood stability.
Energy and Relief from Burnout
Helps reduce feelings of low energy and burnout when folate status is low, especially during times of chronic stress.
Cognitive and Mental Clarity
Supports brain chemistry and one-carbon metabolism that underlie focus, memory, and mental acuity.
Methylation and Cellular Health
GPT said: Nourishes the methylation cycle involved in DNA repair, cell division, and overall brain and body health.
A practical guide to conscious intake
Feeds the methylation cycle that drives your brain chemistry.
With a Fatty Meal
It's best to take Methylated Folate with a full meal. While this B vitamin is water-soluble and can technically be taken on an empty stomach, many people tolerate B-complex supplements better with food. A meal helps mitigate any mild nausea or hot flashes and makes it easier to remember to take your dose. Choose a meal you already eat daily—for example, breakfast or dinner—so your supplement naturally becomes part of your mood and energy routine.
Consistent Daily Intake
The effects of L-5-MTHF are subtle and usually build up over 1–4 weeks. You gradually correct your folate status and support neurotransmitter synthesis; this takes time. Therefore, choose a fixed time each day and stick to it consistently, rather than taking a capsule occasionally when you remember. After a few weeks, you can assess, together with your healthcare provider or based on your own diary, whether your mood, energy, and mental clarity have become more stable.
Optimizing Calcium Absorption
Your brain functions best when folate, B12, B6, and other nutrients are in balance. Therefore, take Methylated Folate as part of a broader diet that includes sufficient protein, B vitamins, and minerals. If you also take other supplements—such as a B-complex or a vitamin D/omega-3 product—you can take them with the same meal, ensuring you don't forget anything and giving your body a consistent supply of cofactors. This optimizes the synergy between folate and the rest of your nutrition plan, instead of relying on just one vitamin.
Take daily
Methylation support works best with consistent daily intake.
Combine with B12
Folate and B12 often work together in these processes; a deficiency of either can affect mood and energy.
Evaluate after 1–4 weeks
Many people notice changes in mood and energy after 1–4 weeks, especially when correcting low folate levels.
Important Health Information
This information comes from leading health authorities like the NIH and is intended to help you make an informed decision about your wellness journey.
Why do people take methylated folate?
Dosage Guidelines
Safety & Interactions
What our community says
Real stories of people like you, finding their peace.
"Ik voel me de hele dag veel alerter en mijn stemming is stabieler. Dit L-5-MTHF supplement is echt een gamechanger voor mijn focus en energie."
"Mijn energieniveau is constanter geworden en ik merk dat mijn gemoedstoestand beter in balans is. Geweldig dat het actieve folaat direct werkt!"
"Geweldige formule! Ik ervaar minder vermoeidheid en voel me mentaal scherper. Het is duidelijk dat het L-5-MTHF goed wordt opgenomen."
"Eindelijk een supplement dat mijn stemming en focus ondersteunt. Goede kwaliteit, merkbaar verschil in mijn dagelijkse energie en helderheid."
"Sinds ik L-5-MTHF gebruik voel ik me minder uitgeput na drukke weken. De actieve vorm van folaat maakt echt het verschil in hoe ik me voel."
"Ik voel me de hele dag veel alerter en mijn stemming is stabieler. Dit L-5-MTHF supplement is echt een gamechanger voor mijn focus en energie."
"Mijn energieniveau is constanter geworden en ik merk dat mijn gemoedstoestand beter in balans is. Geweldig dat het actieve folaat direct werkt!"
"Geweldige formule! Ik ervaar minder vermoeidheid en voel me mentaal scherper. Het is duidelijk dat het L-5-MTHF goed wordt opgenomen."
"Eindelijk een supplement dat mijn stemming en focus ondersteunt. Goede kwaliteit, merkbaar verschil in mijn dagelijkse energie en helderheid."
"Sinds ik L-5-MTHF gebruik voel ik me minder uitgeput na drukke weken. De actieve vorm van folaat maakt echt het verschil in hoe ik me voel."